Effect of proteoglycans on hydroxyapatite growth in vitro: the role of hyaluronan
Biochimica et Biophysica Acta (BBA) - General Subjects, ISSN: 0304-4165, Vol: 1158, Issue: 2, Page: 129-136
1993
- 27Citations
- 18Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations27
- Citation Indexes27
- CrossRef27
- 26
- Captures18
- Readers18
- 18
Article Description
The effect of cartilage proteoglycans on HA seed crystal growth was studied using a system providing constant supersaturation with respect to HA. The monomers were much less effective than the aggregates in reducing the rate of HA growth, which correlates with their affinity for the HA crystals. Hyaluronan, which is a normal constituent of the proteoglycan aggregates, behaved as a strong inhibitor of HA seed crystal growth and had an affinity constant similar to that of proteoglycan aggregates. The results indicate that inhibition of HA seed crystal growth is mediated throught the interaction of hyaluronan with HA crystal surface and that the proteoglycans add to the volume of the adsorbate causing steric hindrance.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/030441659390006T; http://dx.doi.org/10.1016/0304-4165(93)90006-t; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0027907855&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/8399313; http://linkinghub.elsevier.com/retrieve/pii/030441659390006T; http://api.elsevier.com/content/article/PII:030441659390006T?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:030441659390006T?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/030441659390006T; http://dx.doi.org/10.1016/0304-4165%2893%2990006-t; https://dx.doi.org/10.1016/0304-4165%2893%2990006-t
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