EVIDENCE FOR AN EARLY INFLAMMATORY RESPONSE IN THE CENTRAL NERVOUS SYSTEM OF MICE WITH SCRAPIE
Neuroscience, ISSN: 0306-4522, Vol: 74, Issue: 1, Page: 1-5
1996
- 183Citations
- 62Captures
- 1Mentions
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations183
- Citation Indexes183
- 183
- CrossRef147
- Captures62
- Readers62
- 62
- Mentions1
- Blog Mentions1
- Blog1
Article Description
In Alzheimer's disease, the most prevalent of the neurodegenerative diseases, inflammation of the CNS contributes to the pathology and is a target for therapy. [13, 18, 19] In contrast, the group of neurodegenerative conditions known as the Prion Diseases have been widely reported as lacking any inflammatory elements [5, 23] despite the many similarities between the pathologies of Alzheimer's Disease and Prion Diseases. [10] We have found evidence for an inflammatory component in mouse scrapie, characterized by microglial activation and T-lymphocyte recruitment, which appears long before any clinical signs of the disease and spreads along well-defined anatomical pathways. These observations emphasize the potential value of murine scrapie as a model for studying the inflammatory pathology of other neurodegenerative diseases. Copyright © 1996 IBRO. Published by Elsevier Science Ltd.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0306452296002126; http://dx.doi.org/10.1016/0306-4522(96)00212-6; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0029784248&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/8843071; https://linkinghub.elsevier.com/retrieve/pii/0306452296002126; http://dx.doi.org/10.1016/0306-4522%2896%2900212-6; https://dx.doi.org/10.1016/0306-4522%2896%2900212-6
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know