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Mitochondrial monoamine oxidase activity during preneural developmental stages of Bufo bufo

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, ISSN: 0306-4492, Vol: 81, Issue: 2, Page: 319-321
1985
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Metrics Details

  • Citations
    10
    • Citation Indexes
      10

Article Description

1.1. Monoamine oxidase specific activities against PEA and 5-HT have been measured in mitochondria isolated from early embryos of Bufo bufo.2.2. During the early development up to the neural fold stage, MAO activity undergoes a continuous decrease that is more evident when PEA is used as the substrate.3.3. The inhibition patterns of deprenyl and clorgyline demonstrate that, at the neural fold stage, both type A and B MAO are present.4.4. Both in eggs and embryos MAO type A activity appears slightly more sensitive to the inhibitory effect of various concentrations (0.1–2 M) of the denaturing agent urea.

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