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The actions of phorbol esters upon isolated calcium currents of Helix aspersa neurones

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, ISSN: 0306-4492, Vol: 102, Issue: 2, Page: 297-303
1992
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1.1. Voltage-clamp recordings have been made from identified neurones in the suboesophageal ganglia of Helix aspersa.2.2. Calcium currents were isolated pharmacologically and studied under two-electrode voltage-clamp.3.3. PdBu but not PMA caused a transient enhancement followed by an irreversible inhibition of the calcium current.4.4. It is concluded that activation of protein kinase C within these neurones may show selectivity with respect to the exogenous activator used.

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