Immunocytochemical localization of the precursor protein for β-amyloid in the rat central nervous system
Neuron, ISSN: 0896-6273, Vol: 1, Issue: 9, Page: 835-846
1988
- 147Citations
- 18Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations147
- Citation Indexes147
- 147
- CrossRef121
- Captures18
- Readers18
- 18
Article Description
Two rabbit polyclonal antibodies generated against different portions of the amyloid precursor protein were used to localize this protein in normal rat brain. Light and electron microscopic immunohistochemical localizations demonstrate that the protein is widely distributed throughout the neuraxis, with the highest concentrations of immunoreactive neurons occurring in the olfactory bulb, cerebral cortex, septum-diagonal band, globus pallidus, cerebellum, and hippocampus. Immunoreactive astrocytes are also present in the cerebral cortex in relation to both neurons and capillaries. However, immunoreactivity was not observed within the endothelium of the cerebral vasculature. These data demonstrate that the β-amyloid precursor is widely distributed in the CNS and provide further insight into the cellular elements that may be involved in the neuropathological changes associated with Alzheimer's disease.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0896627388901316; http://dx.doi.org/10.1016/0896-6273(88)90131-6; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0024109574&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/3152290; https://linkinghub.elsevier.com/retrieve/pii/0896627388901316; http://dx.doi.org/10.1016/0896-6273%2888%2990131-6; https://dx.doi.org/10.1016/0896-6273%2888%2990131-6
Elsevier BV
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