Synthesis and biology of the rigidified glutamate analogue, trans -2-carboxyazetidine-3-acetic acid ( t -CAA)
Bioorganic & Medicinal Chemistry Letters, ISSN: 0960-894X, Vol: 6, Issue: 21, Page: 2559-2564
1996
- 28Citations
- 4Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Article Description
Chemical approaches to the (−)- and (+)- trans -2-carboxyazetidine-3-acetic acids (−)- 1 and (+)- 1, and their homologues (−)- 2 and (+)- 2, compounds that represent rigidified analogues of glutamate (glu), are reported together with the complete biological characterization of (+)- 1 ( t -CAA) at the known glu recognition sites. t -CAA was found to be an inhibitor of Na + -dependent glu uptake and to act as a kainate receptor ligand.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/0960894X96004647; http://dx.doi.org/10.1016/0960-894x(96)00464-7; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=16044373080&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/0960894X96004647; http://linkinghub.elsevier.com/retrieve/pii/0960894X96004647; http://api.elsevier.com/content/article/PII:0960894X96004647?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:0960894X96004647?httpAccept=text/plain; http://dx.doi.org/10.1016/0960-894x%2896%2900464-7; https://dx.doi.org/10.1016/0960-894x%2896%2900464-7
Elsevier BV
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