Ovarian cancer risk and history of selected medical conditions linked with female hormones
European Journal of Cancer, ISSN: 0959-8049, Vol: 33, Issue: 10, Page: 1634-1637
1997
- 39Citations
- 24Captures
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Metrics Details
- Citations39
- Citation Indexes39
- 39
- CrossRef23
- Captures24
- Readers24
- 24
Article Description
To investigate the role of selected medical conditions on the risk of ovarian cancer, we analysed data from a case-control study. Cases were 971 women below the age of 75 years with histologically confirmed epithelial ovarian cancer, admitted to a network of hospitals including the major teaching and general hospitals in the greater Milan area. Controls were 2758 women admitted to the same network of hospitals for acute, non-gynaecological, non-hormone related, non-neoplastic conditions. Obesity/severe overweight were inversely associated with the risk of ovarian cancer (multivariate relative risk, RR, 0.66, 95% confidence interval, CI, 0.52–0.85). Hyperlipidaemia was also inversely related to ovarian cancer risk, (RR 0.64, 95% CI 0.45–0.89). No relationship emerged between ovarian cancer risk and diabetes (RR 0.80, 95% CI 0.54–1.19), hypertension (RR 0.85, 95% CI 0.68–1.06), thyroid diseases (RR 0.89, 95% CI 0.63–1.13) and cholelithiasis (RR 0.86, 95% CI 0.66–1.12). A decreased frequency of ovarian cancer was seen in women with a history of uterine leiomyomas (RR 0.66, 95% CI 0.47–0.92) and benign ovarian cysts (RR 0.69, 95% CI 0.41–1.13).
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0959804997000117; http://dx.doi.org/10.1016/s0959-8049(97)00011-7; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0031427375&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/9389926; http://linkinghub.elsevier.com/retrieve/pii/S0959804997000117; http://api.elsevier.com/content/article/PII:S0959804997000117?httpAccept=text/xml; http://api.elsevier.com/content/article/PII:S0959804997000117?httpAccept=text/plain; https://linkinghub.elsevier.com/retrieve/pii/S0959804997000117; http://dx.doi.org/10.1016/s0959-8049%2897%2900011-7; https://dx.doi.org/10.1016/s0959-8049%2897%2900011-7
Elsevier BV
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