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Crosstalk

Brenner's Encyclopedia of Genetics, Page: 231-233
2013
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Book Chapter Description

Beyond the major metabolic connections that make up the framework of the metabolic network is metabolic crosstalk, which is the subtle interactions between discrete metabolic processes/pathways. These interactions, which are mediated by metabolites and proteins, coordinate metabolic processes to produce a robust metabolic network. Crosstalk interactions can be identified genetically in vivo and are further characterized with a cross-disciplinary approach. Probing metabolic crosstalk aids in characterizing genes of unknown function and revealing the next tier of metabolic paradigms.

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