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Antioxidants for the Prevention and Treatment of Multiple Sclerosis

Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease, Page: 341-353
2015
  • 8
    Citations
  • 0
    Usage
  • 30
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    8
    • Citation Indexes
      8
  • Captures
    30

Book Chapter Description

Multiple sclerosis is a chronic, inflammatory, demyelinating neurodegenerative disease affecting the central nervous system. Although its etiology remains unknown, it has been hypothesized that a dysregulation of the immune response towards different environmental factors, including nutrition, can promote the disease in genetically predisposed individuals. Accumulating data indicate that oxidative stress can play a role in the pathogenesis and symptom development of MS. As a consequence, the intake of appropriate amounts of antioxidants, such as vitamin A, vitamin E, lipoic acid, and coenzyme Q10, through diet or supplementation can be a promising tool for reducing the risk and slowing the progression of the disease. However, data in literature are still inconclusive; well-designed clinical intervention and prospective studies are warranted in order to assess whether antioxidant intake, in combination with other conventional treatments, might be beneficial in the management of MS.

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