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Physostigmine ☆

Reference Module in Biomedical Sciences
2016
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Book Chapter Description

Physostigmine is a cholinesterase inhibitor belonging to the carbamate class. It is also referred to as an indirectly acting cholinomimetic because, by inhibiting acetylcholinesterase, it potentiates responses to endogenous acetylcholine, which is released from cholinergic nerve endings in the central nervous system and periphery. Physostigmine is a water-soluble tertiary amine, which, unlike quaternary amine carbamates, can enter the central nervous system.

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