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Safety Net Program to Improve Statin Initiation Among Adults With High Low-Density Lipoprotein Cholesterol

American Journal of Preventive Medicine, ISSN: 0749-3797, Vol: 65, Issue: 4, Page: 687-695
2023
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Data on Cardiovascular Diseases and Conditions Reported by Researchers at Southern California Permanente Medical Group (Safety Net Program To Improve Statin Initiation Among Adults With High Low-density Lipoprotein Cholesterol)

2023 NOV 17 (NewsRx) -- By a News Reporter-Staff News Editor at Disease Prevention Daily -- Current study results on Cardiovascular Diseases and Conditions have

Article Description

Despite their effectiveness in reducing low-density lipoprotein cholesterol and cardiovascular disease risk, high-intensity statins are underutilized among adults with low-density lipoprotein cholesterol ≥190 mg/dL. This study determined whether a safety net program (SureNet) facilitating medication and laboratory test orders improved statin initiation and laboratory test completions after (SureNet period: April 2019–September 2021) and before implementation (pre-SureNet period: January 2016–September 2018). Kaiser Permanente Southern California members aged 20–60 years with low-density lipoprotein cholesterol ≥190 mg/dL and no statin use in previous 2–6 months were included in this retrospective cohort study. Statin orders within 14 days and statin fills, laboratory test completions, and improved low-density lipoprotein cholesterol within 180 days of the high low-density lipoprotein cholesterol (pre-SureNet) or outreach (SureNet period) were compared. Analyses were conducted in 2022. Overall, 3,534 and 3,555 adults were eligible for statin initiation during the pre-SureNet and SureNet periods, respectively. Overall, 759 (21.5%) and 976 (27.5%) had a statin approved by their physician during pre-SureNet and SureNet periods, respectively ( p <0.001). After multivariable adjustment for demographics and clinical characteristics, adults during the SureNet period had a higher likelihood of receiving a statin order (prevalence ratio=1.36, 95% CI=1.25, 1.48), filling their statin (prevalence ratio=1.32, 95% CI=1.26, 1.38), completing their laboratories (prevalence ratio=1.41, 95% CI=1.26, 1.58), and improving low-density lipoprotein cholesterol (prevalence ratio=1.21, 95% CI=1.07, 1.37) than in pre-Surenet period. The SureNet program was able to improve prescription orders, fills, laboratory test completions, and lower low-density lipoprotein cholesterol. Optimizing both physician adherence to treatment guidelines; and patient adherence to the program may improve low-density lipoprotein cholesterol lowering.

Bibliographic Details

Mefford, Matthew T; Zhou, Matt; Zhou, Hui; Derakhshan, Hananeh; Harrison, Teresa N; Zia, Mona; Kanter, Michael H; Scott, Ronald D; Imley, Tracy M; Sanders, Mark A; Timmins, Royann; Reynolds, Kristi

Elsevier BV

Medicine

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