Patient-Centered Heart Failure Therapy
The American Journal of Medicine, ISSN: 0002-9343, Vol: 137, Issue: 1, Page: 23-29
2024
- 1Citations
- 9Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Review Description
Simultaneous initiation of quadruple therapy with angiotensin receptor-neprilysin inhibitor, beta-adrenergic receptor blocker, mineralocorticoid receptor antagonist, and sodium glucose cotransporter 2 inhibitor aims at prompt improvement and prevention of readmission in patients hospitalized for heart failure with reduced ejection fraction. However, titration of quadruple therapy is time consuming. Lengthy up-titration of quadruple therapy may negate the benefit of early initiation. Quadruple therapy should start with a sodium glucose cotransporter 2 inhibition and a mineralocorticoid antagonist, as both enable safe decongestion and require minimal or no titration. Depending on the level of decongestion and clinical characteristics, patients receive an angiotensin receptor-neprilysin inhibitor or a beta-adrenergic receptor blocker to be titrated after hospital discharge. Outpatient addition of an angiotensin receptor-neprilysin inhibitor to a beta-adrenergic receptor blocker or vice versa completes the quadruple therapy scheme. By focusing on decongestion and matching intervention to patients’ profile, the present therapeutic sequence allows rapid implementation of quadruple therapy at fully recommended doses.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0002934323006162; http://dx.doi.org/10.1016/j.amjmed.2023.09.018; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85175290119&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/37838238; https://linkinghub.elsevier.com/retrieve/pii/S0002934323006162; https://dx.doi.org/10.1016/j.amjmed.2023.09.018
Elsevier BV
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