Safety of de-escalation of surgical intervention for atypical ductal hyperplasia on percutaneous biopsy: One size does not fit all
The American Journal of Surgery, ISSN: 0002-9610, Vol: 225, Issue: 1, Page: 21-25
2023
- 5Citations
- 6Captures
- 1Mentions
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Most Recent News
Investigators from University of Kansas Health System Report New Data on Hyperplasia (Safety of De-escalation of Surgical Intervention for Atypical Ductal Hyperplasia On Percutaneous Biopsy: One Size Does Not Fit All)
2023 FEB 03 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Medical Devices Daily -- Current study results on HyperplAsia have been published.
Article Description
Oncologic safety of active monitoring (AM) for atypical ductal hyperplasia (ADH) on core-needle biopsy (CNB) is not well defined. We sought to define oncologic outcomes for AM to manage ADH meeting institutional predefined low-risk criteria (LOW). ADH was diagnosed on CNB from 10/2015-03/2020. LOW (pure ADH, size <1 cm, >50% removed by CNB, <3 foci, and no necrosis) patients were offered AM; all others were recommended for surgical excision. Oncologic outcomes were compared for AM and surgery. 111 were included, 21 (19%) meeting LOW. AM occurred in 18 (86%) while 3 elected for excision (with 0% upgrade). Of the 18 LOW in AM, 2 required additional CNB (none at ADH site): 0% were diagnosed with cancer over median 23 month follow-up. There were no missed cancers at ADH site during AM for LOW, confirming the oncologic safety of AM in this select group.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0002961022005931; http://dx.doi.org/10.1016/j.amjsurg.2022.09.044; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85138767240&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/36180303; https://linkinghub.elsevier.com/retrieve/pii/S0002961022005931; https://dx.doi.org/10.1016/j.amjsurg.2022.09.044
Elsevier BV
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