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Gastrointestinal ecosystem and immunological responses in E. coli challenged pigs after weaning fed liquid diets containing whey permeate fermented with different lactic acid bacteria

Animal Feed Science and Technology, ISSN: 0377-8401, Vol: 207, Page: 278-282
2015
  • 30
    Citations
  • 0
    Usage
  • 40
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    30
    • Citation Indexes
      30
  • Captures
    40

Article Description

The objective of this study was to investigate the effect of feeding liquid feed containing whey permeate (WP) fermented with different lactic acid bacteria (LAB) on the microbiota and mucosal immune responses of Escherichia coli F4 inoculated piglets post weaning. The study consisted of 52 weaned piglets allotted to 6 treatments: (1) no infection and no WP (INF − WP − ); (2) infection and no WP (INF + WP − ); (3) infection and non-fermented WP (INF + WP + ); (4) infection and WP fermented with Streptococcus thermophilus and Lactobacillus bulgaricus (INF + WP + LAB1); (5) infection and WP fermented with Lactobacillus plantarum (INF + WP + LAB2); and (6) infection and WP fermented with Weissella viridescens (INF + WP + LAB3). Piglets in groups 2 to 6 were inoculated with E. coli F4 on day 2 and 3 after weaning. Faeces were collected on days 2, 3, 4, 5, 6 and 8 and the pigs were sacrificed on day 11. Digesta and mucosa were collected from the GIT segments. Lactic acid concentration was higher ( P < 0.05) in the stomach of the INF + WP + LAB3 fed piglets than in the other piglets, but the difference was not significant compared to the INF + WP + LAB1 and INF + WP + LAB2 fed piglets. Compared to the control diet, the fermented WP diet tended ( P = 0.069) to lower total coliform and enhanced ( P = 0.050) LAB:coliform ratio in GIT digesta. The faecal LAB:coliform ratio was higher ( P < 0.05) in the INF + WP + LAB3 fed piglets than in the other piglets, but the difference was not significant compared to the INF + WP + LAB2 fed piglets. Intestinal immunoglobulin (Ig) A decreased ( P < 0.05) when feeding WP or W. viridescens -fermented WP. Feeding W. viridescens -fermented WP upregulated ( P < 0.05) ileal interleukin (IL)-10 expression. In conclusion, provision of liquid feed containing W. viridescens -fermented WP improved the intestinal health of E. coli inoculated pigs.

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