Diferencias de estado nutricional, control metabólico y tratamiento de la diabetes tipo 1 en dos décadas
Anales de Pediatría, ISSN: 1695-4033, Vol: 75, Issue: 4, Page: 259-265
2011
- 4Citations
- 36Captures
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Metrics Details
- Citations4
- Citation Indexes4
- CrossRef2
- Captures36
- Readers36
- 19
- 17
Article Description
Describir los cambios en las características antropométricas, control metabólico, tratamiento y prevalencia de sobrepeso en los niños diabéticos en los últimos 20 años. Estudio observacional retrospectivo de dos grupos de niños diagnosticados de DM1 (n = 90) realizado en dos cortes transversales, 1986 y finales del año 2007. Las variables estudiadas fueron: edad, años de DM1, sexo; peso, talla, IMC y sus valores Z; HbA 1c, unidades NGSP/DCCT (%) e IFCC (mmol/mol), y el tratamiento con insulina (tipo, número de dosis, U/día y U/kg/día). En relación con el grupo de 1986, en el grupo de 2007 hay un incremento significativo (p = 0,001) en las variables Z-peso y Z-IMC. Hay una relación negativa entre los años de DM1 y la talla (Z-talla) en el grupo de 1986 (p < 0,05). La HbA 1c es menor en el grupo 2007 (p = 0,001), pero la dosis de insulina (U/día y U/kg/día) es similar en ambos grupos. El número de dosis diarias de insulina es mayor en el grupo 2007 (p < 0,001) y predomina el uso de análogos de la insulina. No se encontró una relación estadísticamente significativa entre la HbA 1c y el tratamiento insulínico (dosis, número de inyecciones y tipo de insulina). La prevalencia de sobrepeso (14,6% vs 2,4%) es significativamente mayor en el grupo de 2007 (p = 0,001). El control metabólico ha mejorado y el uso de múltiples dosis diarias de insulina se ha convertido en la norma, pero ha aumentado la prevalencia de sobrepeso que puede incrementar el riesgo cardiovascular de los niños diabéticos. The aim of this study is to describe changes in anthropometric characteristics, metabolic control, treatment and prevalence of overweight in diabetic children (DM1) from 2007 compared with another similar group from 1986. Observational retrospective study of two groups of diabetic children (n = 90). The collection of variables has been made at two cross-sections, 1986 and 2007. The studied variables were: age, years of DM1, sex, weight, height, BMI (and their Z values), HbA 1c and treatment with insulin (type, number of doses, IU/day and IU/kg/day). In 2007 group there is a significant increase in Z-weight and Z-BMI ( P =.001) when compared with the 1986 group. There was a negative relationship between the years with DM1 and Z-height ( P =.05) in the 1986 group. The value of HbA 1c was lower in the 2007 group ( P =.001), but the dose of insulin (IU/day and IU/kg/day) was similar in both groups. The number of daily doses of insulin was higher in the 2007 group ( P <.001), the use of insulin analogues dominated overall. A statistically significant relationship between HbA 1c and treatment with insulin (dose injections, insulin type) was not found. The prevalence of overweight (14.6% vs 2.4%) was significantly higher in the 2007 Group ( P =.001). The metabolic control (HbA 1c ) had improved and the use of multiple daily doses of insulin has been become the standard, but the prevalence of overweight has increased. We must monitor the emergence of insulin resistance and cardiovascular risk factors in this sensitive population to prevent early cardiovascular disease.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1695403311002633; http://dx.doi.org/10.1016/j.anpedi.2011.04.011; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=80053346865&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/21684229; https://linkinghub.elsevier.com/retrieve/pii/S1695403311002633; https://dx.doi.org/10.1016/j.anpedi.2011.04.011
Elsevier BV
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