Osteoblast adhesion to clodronate-hydroxyapatite composite
Applied Surface Science, ISSN: 0169-4332, Vol: 255, Issue: 2, Page: 308-311
2008
- 6Citations
- 8Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Article Description
The present study combined clodronate, one of bisphosphonates, to the surface of HA scaffold by chelation. The cell culture test and gene expression test were performed and evaluated the effect of clodronate modifying the HA on co-culturing osteoblast with HA scaffold in vitro. Characteristic peaks in XPS and FT-IR spectra indicated clodronate being immobilized on the surface of HA. The cell culture test indicated that the cells actively proliferated on the scaffolds. The results of RT-PCR showed there was no significant difference between two groups in expression of RANKL gene, while the expression of OPG gene showed higher expression in Clodronate-HA group. Clodronate had no obvious effect on the cytocompatibility of HA, and Clodronate-HA might be used as bone scaffold with potential ability to improve osteogenesis.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S016943320801461X; http://dx.doi.org/10.1016/j.apsusc.2008.06.090; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=54349114407&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S016943320801461X; https://dul.usage.elsevier.com/doi/; https://api.elsevier.com/content/article/PII:S016943320801461X?httpAccept=text/xml; https://api.elsevier.com/content/article/PII:S016943320801461X?httpAccept=text/plain; https://dx.doi.org/10.1016/j.apsusc.2008.06.090
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know