PlumX Metrics
Embed PlumX Metrics

Death squads enlisted by the tumour suppressor p53

Biochemical and Biophysical Research Communications, ISSN: 0006-291X, Vol: 331, Issue: 3, Page: 786-798
2005
  • 105
    Citations
  • 0
    Usage
  • 44
    Captures
  • 0
    Mentions
  • 1
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    105
  • Captures
    44
  • Social Media
    1
    • Shares, Likes & Comments
      1
      • Facebook
        1

Review Description

p53 is a tumour suppressor that is found mutated or functionally inactivated in more than half of all human cancers. p53 function is activated by DNA damage, hypoxia, expression of certain oncogenes, and many cytotoxic stimuli. p53 is a transcription factor that regulates expression of target genes which promote apoptotic cell death, cell cycle arrest, cellular senescence, and some other processes. In this review we summarise current knowledge of p53 target genes implicated in apoptosis signalling.

Provide Feedback

Have ideas for a new metric? Would you like to see something else here?Let us know