An in vivo study on the effect of coating stability on osteointegration performance of collagen/hyaluronic acid multilayer modified titanium implants
Bioactive Materials, ISSN: 2452-199X, Vol: 3, Issue: 1, Page: 97-101
2018
- 27Citations
- 40Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations27
- Citation Indexes27
- 27
- CrossRef22
- Captures40
- Readers40
- 40
Article Description
Aseptic loosening of implant is one of the main causes of Ti-based implant failure. In our previous work, a novel stable collagen/hyaluronic acid (Col/HA) multilayer modified titanium coatings (TCs) was developed by layer-by-layer (LBL) covalent immobilization technique, which showed enhanced biological properties compared with TCs that were physically absorbed with Col/HA multilayer in vitro. In this study, a rabbit model with femur condyle defect was employed to compare the osteointegration performance of them. Results indicated that Col/HA multilayer with favourable stability could better facilitate osteogenesis around implants and bone-implant contact. The Col/HA multilayer covalent-immobilized TC may reduce aseptic loosening of implant.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2452199X17300658; http://dx.doi.org/10.1016/j.bioactmat.2017.07.004; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85051590716&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/29744446; https://linkinghub.elsevier.com/retrieve/pii/S2452199X17300658; https://dx.doi.org/10.1016/j.bioactmat.2017.07.004
Elsevier BV
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