Alkylated chitosan-attapulgite composite sponge for rapid hemostasis
Biomaterials Advances, ISSN: 2772-9508, Vol: 153, Page: 213569
2023
- 13Citations
- 16Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations13
- Citation Indexes13
- 13
- CrossRef8
- Captures16
- Readers16
- 16
Article Description
This study reported the development of a composite sponge (ACATS) based on alkylated chitosan (AC) and attapulgite (AT) for rapid hemostasis. The well-designed ACATS, with an optimal AC N-alkylation of 5.9 % and an optimal AC/AT mass ratio of 3:1, exhibited a hierarchical porous structure with a favorable biocompatibility. The ACATS can effectively and rapidly stop the uncontrolled bleeding in 235 ± 64 s with a total blood loss of 8.4 ± 4.0 g in comparison with those of Celox as a positive control (602 ± 101 s and 22.3 ± 2.4 g, respectively) using rabbit carotid artery injury model in vivo. ACATS could rapidly interact with blood and its components, including platelets (PLs), red blood cells (RBCs), and coagulation factors, resulting in these blood components rapidly accumulation and the following thrombus formation and coagulation factors activation.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2772950823002923; http://dx.doi.org/10.1016/j.bioadv.2023.213569; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85166640800&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/37531822; https://linkinghub.elsevier.com/retrieve/pii/S2772950823002923; https://dx.doi.org/10.1016/j.bioadv.2023.213569
Elsevier BV
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