Pinostrobin alleviates testicular and spermatological damage induced by polystyrene microplastics in adult albino rats
Biomedicine & Pharmacotherapy, ISSN: 0753-3322, Vol: 162, Page: 114686
2023
- 26Citations
- 29Captures
- 1Mentions
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations26
- Citation Indexes26
- 26
- CrossRef12
- Captures29
- Readers29
- 29
- Mentions1
- News Mentions1
- News1
Most Recent News
University of Agriculture Reports Findings in Hormones (Pinostrobin alleviates testicular and spermatological damage induced by polystyrene microplastics in adult albino rats)
2023 APR 21 (NewsRx) -- By a News Reporter-Staff News Editor at Middle East Daily -- New research on Hormones is the subject of a
Article Description
Polystyrene microplastics (PS-MPs) have become major environmental pollutants that adversely effects multiple organs specifically testicles. Pinostrobin (PN) is an important flavonoid which, shows several pharmacological potentials. The current study was designed to elucidate the mitigative effects of PN against PS-MPs induced testicular toxicities in rats. 48 male albino rats were randomly distributed into 4 groups, control, PS-MPs group (0.01 mg/kg), PS-MPs + PN group (0.01 mg/kg of PS-MPs; 40 mg/kg of PN) and PN group (40 mg/kg). PS-MPs intoxication substantially lessened the activities of glutathione peroxidase (GPx), glutathione reductase (GSR), superoxide dismutase (SOD) along with catalase (CAT) while, raised the level of malondialdehyde (MDA) as well as reactive oxygen species (ROS). Additionally, PS-MPs reduced luteinizing hormone (LH), plasma testosterone, follicle-stimulating hormone (FSH) concentration, sperm motility, sperm count, expression of steroidogenic enzymes and Bcl-2 (anti-apoptotic protein) along with the count of spermatogenic cells. While, dead sperm count, sperm abnormalities (tail, neck and head), Bax and caspase-3 (apoptotic proteins) expression along with histopathological anomalies were elevated. Moreover, PS-MPs exposure increased the level of inflammatory markers. However, PN treatment considerably decreased oxidative stress (OS) by reducing ROS as well as increased sperm motility and alleviated all the damages induced by the PS-MPs. Therefore, it is concluded that PN may prove a potential therapeutic candidate to restore all the PS-MPs-induced testicular toxicities.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0753332223004742; http://dx.doi.org/10.1016/j.biopha.2023.114686; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85151847770&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/37044025; https://linkinghub.elsevier.com/retrieve/pii/S0753332223004742; https://dx.doi.org/10.1016/j.biopha.2023.114686
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know