Synthesis of dansyl-labeled probe of thiophene analogue of annonaceous acetogenins for visualization of cell distribution and growth inhibitory activity toward human cancer cell lines
Bioorganic & Medicinal Chemistry, ISSN: 0968-0896, Vol: 23, Issue: 6, Page: 1276-1283
2015
- 17Citations
- 22Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations17
- Citation Indexes17
- 17
- CrossRef12
- Captures22
- Readers22
- 22
Article Description
The convergent synthesis of the dansyl-labeled probe of the thiophene-3-carboxamide analogue of annonaceous acetogenins, which shows potent antitumor activity, was accomplished by two asymmetric alkynylations of the 2,5-diformyl THF equivalent with an alkyne having a thiophene moiety and another alkyne tagged with a dansyl group. The growth inhibitory profiles toward 39 human cancer cell lines revealed that the probe retained the biological function of its mother compound, and would be useful for studying cellular activity.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S096808961500053X; http://dx.doi.org/10.1016/j.bmc.2015.01.037; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84923562302&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/25684427; https://linkinghub.elsevier.com/retrieve/pii/S096808961500053X; https://dx.doi.org/10.1016/j.bmc.2015.01.037
Elsevier BV
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