Hippo pathway: Regulation, deregulation and potential therapeutic targets in cancer
Cancer Letters, ISSN: 0304-3835, Vol: 507, Page: 112-123
2021
- 72Citations
- 5Usage
- 42Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations72
- Citation Indexes72
- 72
- CrossRef60
- Usage5
- Abstract Views5
- Captures42
- Readers42
- 42
Article Description
Hippo pathway is a master regulator of development, cell proliferation, stem cell function, tissue regeneration, homeostasis, and organ size control. Hippo pathway relays signals from different extracellular and intracellular events to regulate cell behavior and functions. Hippo pathway is conserved from Protista to eukaryotes. Deregulation of the Hippo pathway is associated with numerous cancers. Alteration of the Hippo pathway results in cell invasion, migration, disease progression, and therapy resistance in cancers. However, the function of the various components of the mammalian Hippo pathway is yet to be elucidated in detail especially concerning tumor biology. In the present review, we focused on the Hippo pathway in different model organisms, its regulation and deregulation, and possible therapeutic targets for cancer treatment.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0304383521001105; http://dx.doi.org/10.1016/j.canlet.2021.03.006; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85102864538&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/33737002; https://linkinghub.elsevier.com/retrieve/pii/S0304383521001105; https://digitalscholar.lsuhsc.edu/sogs_facpubs/10; https://digitalscholar.lsuhsc.edu/cgi/viewcontent.cgi?article=1009&context=sogs_facpubs; https://dx.doi.org/10.1016/j.canlet.2021.03.006
Elsevier BV
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