Rational design and evolutional fine tuning of Saccharomyces cerevisiae for biomass breakdown
Current Opinion in Chemical Biology, ISSN: 1367-5931, Vol: 29, Page: 1-9
2015
- 33Citations
- 114Captures
Metric Options: Counts1 Year3 YearSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations33
- Citation Indexes33
- 33
- CrossRef31
- Captures114
- Readers114
- 114
Review Description
Conferring biomass hydrolysis activity on yeast through genetic engineering has paved the way for the development of groundbreaking processes for producing liquid fuels and commodity chemicals from lignocellulosic biomass. However, the overproduction and misfolding of heterologous and endogenous proteins can trigger cellular stress, increasing the metabolic burden and retarding growth. Improving the efficiency of lignocellulosic breakdown requires engineering of yeast secretory pathway based on system-wide metabolic analysis as well as DNA constructs for enhanced cellulase gene expression with advanced molecular biology tools. Also, yeast is subjected to severe stress due to toxic compounds generated during lignocellulose pretreatment in consolidated saccharification and fermentation processes. The prospect for development of robust yeast strains makes combining evolutionary and rational engineering strategies.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1367593115000678; http://dx.doi.org/10.1016/j.cbpa.2015.06.004; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84934958749&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/26113493; https://linkinghub.elsevier.com/retrieve/pii/S1367593115000678; https://dx.doi.org/10.1016/j.cbpa.2015.06.004
Elsevier BV
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