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Sodium selenite inhibits interleukin-6-mediated androgen receptor activation in prostate cancer cells via upregulation of c-Jun

Clinica Chimica Acta, ISSN: 0009-8981, Vol: 380, Issue: 1, Page: 145-150
2007
  • 20
    Citations
  • 0
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  • 9
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  • 0
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Metric Options:   Counts1 Year3 Year

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Article Description

It has been suggested that interleukin-6 (IL-6) may modulate androgen receptor (AR) action to accelerate prostate cancer (PCa) progression. Selenium compounds are highly recommended as a promising chemopreventive agent for PCa. This study was to determine if selenium can repress IL-6 mediated AR action in PCa progression.

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