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Catecholaminergic Polymorphic Ventricular Tachycardia

Cardiac Electrophysiology Clinics, ISSN: 1877-9182, Vol: 15, Issue: 3, Page: 293-305
2023
  • 4
    Citations
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  • 7
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Metric Options:   Counts1 Year3 Year

Metrics Details

Review Description

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by bidirectional or polymorphic ventricular arrhythmia provoked by exercise or emotion. Most cases are caused by pathogenic variants in the gene encoding the cardiac ryanodine receptor (RYR2). The options for treating patients with CPVT have increased during the years, and evidence suggests that these have led to lower arrhythmic event rates. In addition, numerous potential new therapies are being investigated. In this review, we summarize the state of knowledge on both established and potential future treatment strategies for patients with CPVT and describe our approach to their management.

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