Two-photon excitation photosensitizers for photodynamic therapy: From small-molecules to nano-complex systems
Coordination Chemistry Reviews, ISSN: 0010-8545, Vol: 506, Page: 215711
2024
- 11Citations
- 22Captures
- 1Mentions
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Most Recent News
Researchers from Ajou University Report Recent Findings in Phototherapy (Two-photon Excitation Photosensitizers for Photodynamic Therapy: From Small-molecules To Nano-complex Systems)
2024 MAY 07 (NewsRx) -- By a News Reporter-Staff News Editor at South Korea Daily Report -- Investigators publish new report on Drugs and Therapies
Review Description
Two-photon excitation photodynamic therapy (TP-PDT), which uses near-infrared light (>700 nm) as an excitation source, is an essential approach for modern deep-tissue phototherapy. TP offers the advantage of enhanced spatial precision, which enables targeted treatment without harming the surrounding healthy tissue. This review focuses on the recent developments in TP-activating photosensitizers (TP-PSs), which are key agents in TP-PDT. We begin with a brief description of the concept of TP-PDT and then we summarize the recent developments in various types of TP-PSs. We introduce various types of small-molecule-based photosensitizers, specific organelle targeting, and activation strategies using biomolecules, transition metal complexes, and nanocomplex systems. For clarity, we have provided a limited number of TP-PSs characterized by systematic and well-structured approaches. This reveals the promising future of TP-PDT as an innovative therapeutic approach.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0010854524000572; http://dx.doi.org/10.1016/j.ccr.2024.215711; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85185375501&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S0010854524000572; https://dx.doi.org/10.1016/j.ccr.2024.215711
Elsevier BV
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