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Hydrogels containing composite of Ag 3 Sn intermetallic compounds and tin oxide for enhanced anti-bacterial and wound healing

Chemical Engineering Journal, ISSN: 1385-8947, Vol: 494, Page: 153051
2024
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  • Mentions
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    • News Mentions
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Most Recent News

Findings on Bacterial Infections and Mycoses Detailed by Investigators at Xiamen University (Hydrogels Containing Composite of Ag 3 Sn Intermetallic Compounds and Tin Oxide for Enhanced Anti-bacterial and Wound Healing)

2024 AUG 19 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Drug Daily -- Current study results on Bacterial Infections and Mycoses have

Article Description

Bacterial infection has become a serious clinical challenge and a great threat to human health due to antibiotic resistance. Therefore, developing new antimicrobial agents are essential. It is noteworthy that the new antibacterial strategy, photocatalytic antimicrobial therapy, addresses the issue of bacterial resistance. Metal oxides, particular tin oxide, hold great promise in the photocatalytic antimicrobial properties. In addition, noble metal Ag has an excellent improvement effect on the visible light photocatalytic activity of photocatalyst. However, the pure Ag has some shortcomings, such as instability at high temperature. Here, Ag 3 Sn intermetallic compounds are synthesized, wherein the tin atoms are naturally oxidized to SnO x in the air. The composites (Ag 3 Sn-SnO x ) possess a narrow band gap energy, rendering it suitable as a photocatalytic material responsive to visible light. Meanwhile, Ag 3 Sn-SnO x will slowly release Ag and play a long-term antibacterial effect. In addition, carboxymethyl chitosan-hyaluronic acid hydrogel are synthesized via amidation reaction, and Ag 3 Sn-SnO x is loaded into the hydrogel (Ag 3 Sn-SnO x @Gel), which is also endowed with ability to promote the proliferation and migration of fibroblasts. Coupled with its good biosafety profile, Ag 3 Sn-SnO x @Gel is expected to emerge as a reliable and effective alternative to the currently used clinical wound dressings.

Bibliographic Details

Baoyin Chen; Caihong He; Jingbo Zhang; Yuting Du; Jiaqi Guo; Xuewen Zhang; Qipeng Lu; Bing Wang; Xuan Zhu; Dengyue Chen

Elsevier BV

Chemistry; Environmental Science; Chemical Engineering; Engineering

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