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Functionalized vinyldiazo compounds: New players in asymmetric catalysis

Chem Catalysis, ISSN: 2667-1093, Vol: 3, Issue: 10, Page: 100770
2023
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Article Description

In this issue of Chem Catalysis, Doyle et al. prepare functionalized vinyldiazoacetates through base-promoted ring opening of 5-alkyl-1,2,3,triazine-1-oxides. These diazo compounds engage in several metal-catalyzed enantioselective transformations. The high degree of functionalization of the products and the excellent enantiocontrol position these new diazo compounds as promising reagents in asymmetric catalysis.

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