Biological applications of LbL multilayer capsules: From drug delivery to sensing
Advances in Colloid and Interface Science, ISSN: 0001-8686, Vol: 207, Issue: 1, Page: 139-154
2014
- 129Citations
- 154Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations129
- Citation Indexes129
- 129
- CrossRef101
- Captures154
- Readers154
- 154
Review Description
Polyelectrolyte multilayer (PEM) capsules engineered with active elements for targeting, labeling, sensing and delivery hold great promise for the controlled delivery of drugs and the development of new sensing platforms. PEM capsules composed of biodegradable polyelectrolytes are fabricated for intracellular delivery of encapsulated cargo (for example peptides, enzymes, DNA, and drugs) through gradual biodegradation of the shell components. PEM capsules with shells responsive to environmental or physical stimuli are exploited to control drug release. In the presence of appropriate triggers ( e.g., pH variation or light irradiation) the pores of the multilayer shell are unlocked, leading to the controlled release of encapsulated cargos. By loading sensing elements in the capsules interior, PEM capsules sensitive to biological analytes, such as ions and metabolites, are assembled and used to detect analyte concentration changes in the surrounding environment. This Review aims to evaluate the current state of PEM capsules for drug delivery and sensing applications.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0001868614000712; http://dx.doi.org/10.1016/j.cis.2014.02.014; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84901237430&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/24625331; https://linkinghub.elsevier.com/retrieve/pii/S0001868614000712; https://dx.doi.org/10.1016/j.cis.2014.02.014
Elsevier BV
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