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Solubilization of supported lipid membranes by octyl glucoside observed by time-lapse atomic force microscopy

Colloids and Surfaces B: Biointerfaces, ISSN: 0927-7765, Vol: 55, Issue: 2, Page: 179-184
2007
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Article Description

Detergents are very useful for the purification of membrane proteins. A good detergent for protein extraction has to prevent denaturation by unfolding, and to avoid aggregation. Therefore, gaining access to the mechanism of biomembranes’ solubilization by detergents is crucial in biochemical research. Among the wide range of detergents used to purify membrane proteins, n -octyl β- d -glucopyranoside (OG) is one of the most important as it can be easily removed from final protein extracts.

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