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Actin-Filament Disassembly: It Takes Two to Shrink Them Fast

Current Biology, ISSN: 0960-9822, Vol: 25, Issue: 11, Page: R450-R452
2015
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Article Description

Actin-filament disassembly is indispensable for replenishing the pool of polymerizable actin and allows continuous dynamic remodelling of the actin cytoskeleton. A new study now reveals that ADF/cofilin preferentially dismantles branched networks and provides new insights into the collaborative work of ADF/cofilin and Aip1 on filament disassembly at the molecular level.

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