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Epithelial Polarity: Dual Lkb1 Pathways Regulate Apical Microvilli

Developmental Cell, ISSN: 1534-5807, Vol: 16, Issue: 4, Page: 491-492
2009
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Article Description

The Lkb1/Strad/Mo25 complex can polarize single epithelial cells, leading to the formation of a brush border containing microvilli on the apical surface. In this issue of Developmental Cell, ten Klooster et al. show that the Lkb1/Strad/Mo25 complex mediates two separate pathways, and that both are required for assembly of apical microvilli.

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