Equilibrium and release properties of hyaluronic acid–drug complexes
European Journal of Pharmaceutical Sciences, ISSN: 0928-0987, Vol: 49, Issue: 4, Page: 588-594
2013
- 19Citations
- 35Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations19
- Citation Indexes19
- 19
- CrossRef17
- Captures35
- Readers35
- 35
Article Description
With the aim to provide more rational basis about the potentiality of hyaluronic acid (or hyaluronan) as drug carrier a set of ionic complexes of its acid form (HA) and its sodium salt (NaHA) with three model drugs (D) (atenolol, propranolol and lidocaine) were prepared. Besides NaHA subjected to hyalurodinase depolimerization (NaHA d ) was also used. Transparent dispersions were obtained. They exhibited negative electrokinetic potential and a high degree of counterionic condensation with affinity constants (log K cc ) in the range of 5.8–6.1 for propranolol complexes (p K a 9.45) and 4.0–4.6 for lidocaine ones (p K a 7.92).
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0928098713001619; http://dx.doi.org/10.1016/j.ejps.2013.04.023; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84879465442&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/23659801; https://linkinghub.elsevier.com/retrieve/pii/S0928098713001619; https://dx.doi.org/10.1016/j.ejps.2013.04.023
Elsevier BV
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