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Immunocyt and the HA-HAase Urine Tests for the Detection of Bladder Cancer: A Side-by-Side Comparison

European Urology, ISSN: 0302-2838, Vol: 46, Issue: 4, Page: 466-471
2004
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Article Description

Objectives: The reliable detection of bladder cancer from urine specimen remains an unsolved problem. Especially superficial bladder cancer can be missed with urine tests. We assessed the sensitivity and specificity of the commercial Immunocyt test in a side-by-side comparison with the HA-HAase urine test and cytology. The Immunocyt test measures the immunocytological expression of sulfated mucin-glycoproteins and glycosylated forms of the carcinoembryonic antigen in urine. With the HA-HAase urine test the level of hyaluronic acid (HA) and its degrading enzyme hyaluronidase (HAase) are measured in an ELISA-like test.

Bibliographic Details

Hautmann, Stefan; Toma, Marieta; Lorenzo Gomez, Maria Fernanda; Friedrich, Martin G; Jaekel, Torsten; Michl, Uwe; Schroeder, Gretchen L; Huland, Hartwig; Juenemann, Klaus-Peter; Lokeshwar, Vinata B

Elsevier BV

Medicine

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