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Four undescribed sesquiterpenes from Artemisia mongolica and their anti-inflammatory activity

Fitoterapia, ISSN: 0367-326X, Vol: 177, Page: 106093
2024
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Article Description

Four undescribed sesquiterpene compounds ( 1 – 4 ) and six known compounds ( 5 – 10 ) were isolated from A. mongolica. Furthermore, compound 5 was a new natural product previously synthesized. The LPS-stimulated BV2 cells were used as a model to evaluate the anti-inflammatory activity of the isolated compounds, among them, compounds 2, 3 and 4 showed significant inhibition of NO levels with IC 50 values of 27.48, 27.39 and 24.96 μM, respectively.

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