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Ultrasensitive functionalized CeO 2 /ZnO nanocomposite sensor for determination of a prohibited narcotic in sports pethidine hydrochloride

Heliyon, ISSN: 2405-8440, Vol: 9, Issue: 5, Page: e15793
2023
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Reports on Nanocomposites Findings from King Saud University Provide New Insights (Ultrasensitive functionalized CeO2/ZnO nanocomposite sensor for determination of a prohibited narcotic in sports pethidine hydrochloride)

2023 MAY 12 (NewsRx) -- By a News Reporter-Staff News Editor at Sports Research Daily -- New study results on nanocomposites have been published. According

Article Description

The extraordinary features of cerium oxide (CeO 2 ) and zinc oxide (ZnO) nanostructures have encouraged substantial attention to those nanocomposites as probable electroactive complexes for sensing and biosensing purposes. In this study, an advanced novel factionalized CeO 2 /ZnO nanocomposite-aluminum wire membrane sensor was designed to assess pethidine hydrochloride (PTD) in commercial injection samples. Pethidine-reineckate (PTD-RK) was formed by mixing pethidine hydrochloride and ammonium reineckate (ARK) in the presence of polymeric matrix (polyvinyl chloride) and o -nitrophenyl octyl ether as a fluidizing agent. The functionalized nanocomposite sensor displayed a fast dynamic response and wide linearity for the detection of PTD. It also revealed excellent selectivity and sensitivity, high accuracy, and precision for the determination and quantification of PTD when compared with the unmodified sensor PTD-RK. The guidelines of analytical methodology requirements were obeyed to improve the suitability and validity of the suggested potentiometric system according to several criteria. The developed potentiometric system was suitable for the determination of PTD in bulk powder and commercial products.

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