Analysis of changes in antibiotic resistance in the human body using an in vitro digestion model incorporating human gut microbiota
Heliyon, ISSN: 2405-8440, Vol: 9, Issue: 5, Page: e16128
2023
- 3Citations
- 12Captures
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Most Recent News
Research from Gyeongsang National University in the Area of Science and Technology Published (Analysis of changes in antibiotic resistance in the human body using an in vitro digestion model incorporating human gut microbiota)
2023 JUN 01 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Drug Daily -- Research findings on science and technology are discussed in
Article Description
Residual antibiotics may affect human health by increasing challenges related to infection treatment due to antibiotic resistance development. Hence, determining whether residual antibiotics in the body can lead to antibiotic resistance is important. We developed a model to predict possible antibiotic resistance caused by residual antibiotics by simulating human digestion in vitro. Increased antibiotic resistance was found to be dependent on the digestion process. Ethical prediction of antibiotic resistance using fewer animals and no humans was possible by simulating the internal environment. Thus, preliminary studies to monitor antibiotic resistance that can affect human health may be safely conducted using this model.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2405844023033352; http://dx.doi.org/10.1016/j.heliyon.2023.e16128; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85159359979&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/37251864; https://linkinghub.elsevier.com/retrieve/pii/S2405844023033352; https://dx.doi.org/10.1016/j.heliyon.2023.e16128
Elsevier BV
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