Identification of peptides from camel milk that inhibit starch digestion
International Dairy Journal, ISSN: 0958-6946, Vol: 141, Page: 105620
2023
- 4Citations
- 13Captures
- 1Mentions
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Most Recent News
Investigators from University of Alberta Have Reported New Data on Peptides (Identification of Peptides From Camel Milk That Inhibit Starch Digestion)
2023 JUN 02 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Life Science Daily -- Research findings on Peptides and Proteins - Peptides
Article Description
The inhibition of starch digestion activities by peptides derived from camel milk proteins was determined and the effect of their amino acids charge and/or hydrophobicity was assessed. Starch digestion by pancreatic and brush border enzymes was assessed in vitro with a peptide to starch ratio of 1:3 (w/w). Hydrolysed whey proteins were more inhibitory than hydrolysed casein. Successive chromatographic separation of peptides enriched positively charged peptides with hydrophobic amino acids. Whey protein hydrolysate inhibited starch hydrolysis by 16%; peptide fractions recovered after CEX and HIC inhibited starch hydrolysis by 33–36%. Peptides in the active fractions were identified by LC–MS/MS and the inhibitory activity of 6 synthetic peptides was evaluated. Two of these six peptides, LALDIEIATYR and VLDELTLAR, inhibited starch hydrolysis by 34–37%. In conclusion, specific peptides that are produced before or during in vitro digestion can inhibit starch digestion and may moderate postprandial blood glucose levels in vivo.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0958694623000390; http://dx.doi.org/10.1016/j.idairyj.2023.105620; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85149440646&origin=inward; https://linkinghub.elsevier.com/retrieve/pii/S0958694623000390; https://dx.doi.org/10.1016/j.idairyj.2023.105620
Elsevier BV
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