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Identification of peptides from camel milk that inhibit starch digestion

International Dairy Journal, ISSN: 0958-6946, Vol: 141, Page: 105620
2023
  • 4
    Citations
  • 0
    Usage
  • 13
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    4
    • Citation Indexes
      4
  • Captures
    13
  • Mentions
    1
    • News Mentions
      1
      • News
        1

Most Recent News

Investigators from University of Alberta Have Reported New Data on Peptides (Identification of Peptides From Camel Milk That Inhibit Starch Digestion)

2023 JUN 02 (NewsRx) -- By a News Reporter-Staff News Editor at NewsRx Life Science Daily -- Research findings on Peptides and Proteins - Peptides

Article Description

The inhibition of starch digestion activities by peptides derived from camel milk proteins was determined and the effect of their amino acids charge and/or hydrophobicity was assessed. Starch digestion by pancreatic and brush border enzymes was assessed in vitro with a peptide to starch ratio of 1:3 (w/w). Hydrolysed whey proteins were more inhibitory than hydrolysed casein. Successive chromatographic separation of peptides enriched positively charged peptides with hydrophobic amino acids. Whey protein hydrolysate inhibited starch hydrolysis by 16%; peptide fractions recovered after CEX and HIC inhibited starch hydrolysis by 33–36%. Peptides in the active fractions were identified by LC–MS/MS and the inhibitory activity of 6 synthetic peptides was evaluated. Two of these six peptides, LALDIEIATYR and VLDELTLAR, inhibited starch hydrolysis by 34–37%. In conclusion, specific peptides that are produced before or during in vitro digestion can inhibit starch digestion and may moderate postprandial blood glucose levels in vivo.

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