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Changes in CD4 + CD25 + Foxp3 + Regulatory T Cells in Relation to Aging and Lung Tumor Incidence

International Journal of Gerontology, ISSN: 1873-9598, Vol: 6, Issue: 3, Page: 187-191
2012
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Metric Options:   Counts1 Year3 Year

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Article Description

CD4 + CD25 + Foxp3 + regulatory T (Treg) cells mediate immunosuppression and play an important role in tumor immune evasion. Studies have demonstrated that this cell population represents an aging-related change. It is not clear whether this change leads to higher tumor incidence in the elderly. We investigated changes in CD4 + CD25 + Foxp3 + Treg cells in relation to aging and tumor incidence.

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