Spinal Cord Dose Tolerance to Stereotactic Body Radiation Therapy
International Journal of Radiation Oncology*Biology*Physics, ISSN: 0360-3016, Vol: 110, Issue: 1, Page: 124-136
2021
- 125Citations
- 246Captures
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations125
- Citation Indexes125
- 125
- CrossRef47
- Captures246
- Readers246
- 246
Article Description
Spinal cord tolerance data for stereotactic body radiation therapy (SBRT) were extracted from published reports, reviewed, and modelled. For de novo SBRT delivered in 1 to 5 fractions, the following spinal cord point maximum doses (D max ) are estimated to be associated with a 1% to 5% risk of radiation myelopathy (RM): 12.4 to 14.0 Gy in 1 fraction, 17.0 Gy in 2 fractions, 20.3 Gy in 3 fractions, 23.0 Gy in 4 fractions, and 25.3 Gy in 5 fractions. For reirradiation SBRT delivered in 1 to 5 fractions, reported factors associated with a lower risk of RM include cumulative thecal sac equivalent dose in 2 Gy fractions with an alpha/beta of 2 (EQD2 2 ) D max ≤70 Gy; SBRT thecal sac EQD2 2 D max ≤25 Gy, thecal sac SBRT EQD2 2 D max to cumulative EQD2 2 D max ratio ≤0.5, and a minimum time interval to reirradiation of ≥5 months. Larger studies containing complete institutional cohorts with dosimetric data of patients treated with spine SBRT, with and without RM, are required to refine RM risk estimates.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S0360301619338623; http://dx.doi.org/10.1016/j.ijrobp.2019.09.038; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85074778645&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/31606528; https://linkinghub.elsevier.com/retrieve/pii/S0360301619338623; https://dx.doi.org/10.1016/j.ijrobp.2019.09.038; https://www.redjournal.org/article/S0360-3016(19)33862-3/abstract; http://www.redjournal.org/article/S0360301619338623/abstract; http://www.redjournal.org/article/S0360301619338623/fulltext; http://www.redjournal.org/article/S0360301619338623/pdf; https://www.redjournal.org/article/S0360-3016(19)33862-3/fulltext; https://www.redjournal.org/article/S0360-3016(19)33862-3/fulltext?rss=yes
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know