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COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome

Immunity, ISSN: 1074-7613, Vol: 52, Issue: 5, Page: 731-733
2020
  • 630
    Citations
  • 0
    Usage
  • 999
    Captures
  • 10
    Mentions
  • 104
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    630
  • Captures
    999
  • Mentions
    10
    • News Mentions
      8
      • News
        8
    • References
      2
      • Wikipedia
        2
  • Social Media
    104
    • Shares, Likes & Comments
      104
      • Facebook
        104

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Introduction Coronavirus disease 2019 (COVID-19) was initially identified in December 2019 in the city of Wuhan, China. Since then, it has rapidly spread across the

Article Description

Zhou et al. ( Nature ) and Hoffmann et al. ( Cell ) identify ACE2 as a SARS-CoV-2 receptor, and the latter show its entry mechanism depends on cellular serine protease TMPRSS2. These results may explain proinflammatory cytokine release via the associated angiotestin II pathway and a possible therapeutic target via the IL-6-STAT3 axis.

Bibliographic Details

Hirano, Toshio; Murakami, Masaaki

Elsevier BV

Medicine; Immunology and Microbiology

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