Sulfonamide functional head on short-chain perfluorinated substance drives developmental toxicity
iScience, ISSN: 2589-0042, Vol: 25, Issue: 2, Page: 103789
2022
- 41Citations
- 57Captures
- 1Mentions
Metric Options: CountsSelecting the 1-year or 3-year option will change the metrics count to percentiles, illustrating how an article or review compares to other articles or reviews within the selected time period in the same journal. Selecting the 1-year option compares the metrics against other articles/reviews that were also published in the same calendar year. Selecting the 3-year option compares the metrics against other articles/reviews that were also published in the same calendar year plus the two years prior.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations41
- Citation Indexes39
- 39
- Policy Citations2
- Policy Citation2
- Captures57
- Readers57
- 57
- Mentions1
- News Mentions1
- News1
Most Recent News
Sulfonamide Functional Head on Short-Chain Perfluorinated Substance Drives Developmental Toxicity
By Yvonne Rericha, Dunping Cao, Lisa Truong, Michael T. Simonich, Jennifer A. Field, and Robyn L. Tanguay iScience January 25, 2022 DOI: 10.1016/j.isci.2022.103789 Per- and
Article Description
Per- and polyfluoroalkyl substances (PFAS) are ubiquitously detected in environmental and biological samples and cause adverse health effects. Studies have predominately focused on long-chain PFAS, with far fewer addressing short-chain alternatives. This study leveraged embryonic zebrafish to investigate developmental toxicity of a short-chain series: perfluorobutane sulfonate (PFBS), perfluoropentanoic acid (PFPeA), perfluorobutane sulfonamide (FBSA), and 4:2 fluorotelomer sulfonic acid (4:2 FTS). Following static exposures at 8 h postfertilization (hpf) to each chemical (1–100 μM), morphological and behavioral endpoints were assessed at 24 and 120 hpf. Only FBSA induced abnormal morphology, while exposure to all chemicals caused aberrant larval behavior. RNA sequencing at 48 hpf following 47 μM exposures revealed only FBSA significantly disrupted normal gene expression. Measured tissue concentrations were FBSA > PFBS > 4:2 FTS > PFPeA. This study demonstrates functional head groups impact bioactivity and bioconcentration.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2589004222000591; http://dx.doi.org/10.1016/j.isci.2022.103789; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85123860912&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/35146398; https://linkinghub.elsevier.com/retrieve/pii/S2589004222000591; https://dx.doi.org/10.1016/j.isci.2022.103789
Elsevier BV
Provide Feedback
Have ideas for a new metric? Would you like to see something else here?Let us know