Determinants of Endogenous Fibrinolysis in Whole Blood Under High Shear in Patients With Myocardial Infarction
JACC: Basic to Translational Science, ISSN: 2452-302X, Vol: 7, Issue: 11, Page: 1069-1082
2022
- 7Citations
- 9Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Metrics Details
- Citations7
- Citation Indexes7
- CrossRef1
- Captures9
- Readers9
Article Description
Hypofibrinolysis is a recently-recognized risk factor for recurrent cardiovascular events in patients with ST-segment elevation myocardial infarction (STEMI), but the mechanistic determinants of this are not well understood. In patients with STEMI, we show that the effectiveness of endogenous fibrinolysis in whole blood is determined in part by fibrinogen level, high sensitivity C-reactive protein, and shear-induced platelet reactivity, the latter directly related to the speed of thrombin generation. Our findings strengthen the evidence for the role of cellular components and bidirectional crosstalk between coagulatory and inflammatory pathways as determinants of hypofibrinolysis.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2452302X22002145; http://dx.doi.org/10.1016/j.jacbts.2022.05.007; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85141777397&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/36687271; https://linkinghub.elsevier.com/retrieve/pii/S2452302X22002145; https://dx.doi.org/10.1016/j.jacbts.2022.05.007
Elsevier BV
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