Different Patterns of Foods Triggering FPIES in Germany
The Journal of Allergy and Clinical Immunology: In Practice, ISSN: 2213-2198, Vol: 10, Issue: 4, Page: 1063-1069
2022
- 19Citations
- 49Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations19
- Citation Indexes19
- 19
- Captures49
- Readers49
- 49
Article Description
Food protein–induced enterocolitis syndrome (FPIES) is a non–IgE-mediated gastrointestinal food allergy mainly affecting infants and young children. Allergic FPIES reactions differ from IgE-mediated food allergies, for example, regarding elicitors and clinical course. The aim of our study was to describe causative agents and development of tolerance in German children with FPIES. We conducted a retrospective survey on children with FPIES from 14 centers in Germany assessing a 6-year period. We analyzed 142 patients with 190 FPIES reactions, 130 of which met acute FPIES criteria and 60 were defined as chronic FPIES. The most frequent eliciting food for acute FPIES was cow’s milk, followed by fish, vegetables (eg, potato, pumpkin), meats (eg, beef), and grains. A total of 119 children reacted to 1 food only, 16 children to 2 or 3 foods, and 7 children to ≥4 foods. In chronic FPIES, all but 4 exclusively breastfed infants reacted to cow’s milk feeding. IgE sensitization to the triggering food was found in 21 of 152 (14%) cases. Two children developed additional IgE-mediated symptoms upon a food challenge. Time to proof of tolerance was shortest in cow’s milk–induced FPIES, and it was shorter in chronic than in acute FPIES. In our national survey, we identified triggers for acute FPIES that partially differ from those reported internationally. Mainly foods introduced early in infant nutrition triggered acute reactions. Time to proven tolerance was shown to be contingent on FPIES symptomatology and on the triggering food. These data should be considered regarding nutritional advice for infants with FPIES.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2213219821013726; http://dx.doi.org/10.1016/j.jaip.2021.11.033; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85122477548&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/34942384; https://linkinghub.elsevier.com/retrieve/pii/S2213219821013726; https://dx.doi.org/10.1016/j.jaip.2021.11.033
Elsevier BV
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