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Cytomegalovirus-encoded homologs of G protein-coupled receptors and chemokines

Journal of Clinical Virology, ISSN: 1386-6532, Vol: 35, Issue: 3, Page: 343-348
2006
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Article Description

Cytomegaloviruses (CMVs) have developed various sophisticated strategies to manipulate and evade the defense mechanisms of their hosts. Among the CMV genes that are predicted to be involved in these strategies are genes that encode mimics of cellular proteins, such as G protein-coupled receptors (GPCRs) and chemokines (CKs). These genes may have been pirated from the host genome during the long co-evolution of virus and host.

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