Exploring the antioxidant properties of semaglutide: A comprehensive review
Journal of Diabetes and its Complications, ISSN: 1056-8727, Vol: 38, Issue: 12, Page: 108906
2024
- 1Citations
- 14Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
Citation Benchmarking is provided by Scopus and SciVal and is different from the metrics context provided by PlumX Metrics.
Review Description
Patients with diabetes commonly experience an aberrant production of free radicals and weakened antioxidative defenses, making them highly susceptible to oxidative stress development. This, in turn, can induce and promote diabetic complications. Therefore, utilizing antidiabetic agents with antioxidative properties can offer dual benefits by addressing hyperglycemia and reducing oxidative damage. Semaglutide, a recently approved oral form of glucagon-like peptide-1 (GLP-1) analogues, has shown potent antidiabetic effects. Additionally, recent studies have suggested that it possesses antioxidative properties. However, the exact effects and the molecular pathways involved are not well understood. In this review, we present the latest findings on the antioxidative impacts of semaglutide and draw conclusions about the mechanisms involved.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S1056872724002320; http://dx.doi.org/10.1016/j.jdiacomp.2024.108906; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85209154825&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/39549371; https://linkinghub.elsevier.com/retrieve/pii/S1056872724002320
Elsevier BV
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