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More accurate and more efficient: Penicillinase-immobilized phase-change microcapsules for detection and removal of penicillins under microenvironmental thermal management

Journal of Environmental Chemical Engineering, ISSN: 2213-3437, Vol: 11, Issue: 1, Page: 109148
2023
  • 6
    Citations
  • 0
    Usage
  • 3
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    6
  • Captures
    3
  • Mentions
    1
    • News Mentions
      1
      • 1

Most Recent News

Findings from Beijing University of Chemical Technology Provide New Insights into Proteomics (More Accurate and More Efficient: Penicillinase-immobilized Phase-change Microcapsules for Detection and Removal of Penicillins Under ...)

2023 AUG 01 (NewsRx) -- By a News Reporter-Staff News Editor at Proteomics Daily -- Investigators publish new report on Proteomics. According to news reporting

Article Description

Aiming at a high thermal sensitivity of penicillinase (Pen X) in the enzyme-catalyzed hydrolytic reaction of penicillins, we developed a novel type of Pen X-immobilized phase-change microcapsules with a thermo-temperature regulation function for enhancing the detection accuracy and removal efficiency of penicillins under high temperature environments. The microcapsules were constructed by microencapsulating n -docosane in a SiO 2 shell, followed by decorating a biocompatible chitosan coating layer on the shell surface and then immobilizing Pen X through covalent bonding. The resultant Pen X-immobilized microcapsules exhibit a well-defined core-shell microstructure and a regular spherical morphology, together with the desired chemical compositions and structures. The microcapsules present a high heat storage capacity of over 125 J/g to regulate their microenvironmental temperature through reversible phase transitions by their n -docosane core. This enables the Pen X-immobilized microcapsules to achieve a higher enzyme activity at high assay temperatures compared to conventional immobilized Pen X, resulting in a high removal rate of 94.71 % for Pen G elimination and an extremely high recovery rate of nearly 100 % for Pen G determination. Based on their superior biocatalytic capability at high temperatures, the Pen X-immobilized microcapsules developed in this study exhibit great application potential for high-accurate detection and high-efficient removal of penicillins in harsh conditions.

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