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Peptidomics approaches for meat authentication employing rapid in-solution GELFrEE fractionation and MALDI-TOF MS

Journal of Food Composition and Analysis, ISSN: 0889-1575, Vol: 121, Page: 105349
2023
  • 7
    Citations
  • 0
    Usage
  • 17
    Captures
  • 1
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    7
    • Citation Indexes
      7
  • Captures
    17
  • Mentions
    1
    • News Mentions
      1
      • News
        1

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Article Description

A rapid and highly reproducible gel-eluted liquid fraction entrapment electrophoresis (GELFrEE) coupled with MALDI-TOF mass spectrometry (MS) is proposed for authenticating adulteration of water buffalo meat with pork. The GELFrEE offers novel in-solution protein fractionation with a dynamic range from 3.5 to 500 kDa and the specificity sufficient to be implemented effectively for the identification of water buffalo and pork-specific peptides derived from myoglobin (‘HPGDFGADAQGAMSK’, ‘HPSDFGADAQAAMSK’) and carbonic anhydrase-3 (‘GGPLTAAYR’, ‘GGPLAAPYR’) demonstrating their potential as heat-stable markers for meat authentication including commercial samples. The GELFrEE and MS-based approach efficiently authenticated raw and heat-processed meat and meat mixes up to 0.5 % (w/w) level. The quick extraction protocol and rapid fractionation by GELFrEE offer better solutions for routine MS-based approaches to address global meat fraud issues.

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