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Effects of Korean black raspberry supplementation on oxidative stress and plasma antioxidant capacity in healthy male smokers

Journal of Functional Foods, ISSN: 1756-4646, Vol: 16, Page: 393-402
2015
  • 15
    Citations
  • 0
    Usage
  • 47
    Captures
  • 0
    Mentions
  • 0
    Social Media
Metric Options:   Counts1 Year3 Year

Metrics Details

  • Citations
    15
    • Citation Indexes
      15
  • Captures
    47

Article Description

Oxidative stress has been implicated in the pathophysiology of chronic diseases and cigarette smoking is known to be one of the major sources of oxidants. In this study, we investigated whether Korean black raspberry (BR) supplementation could reduce smoke-induced oxidative stress in healthy male smokers. Thirty nine healthy male smokers received either 30 g of freeze-dried BR or placebo for four weeks. Anthropometric and dietary data, smoking history, blood lipid profiles, lipid peroxidation, DNA damage, and antioxidant enzyme activities were assessed at baseline and after supplementation. There was no difference of age, smoking history, anthropometry, and nutrient intake between groups. BR supplementation had no effect on plasma lipid profiles, LDL oxidation, and DNA damage. However, it significantly increased the activity of the antioxidant enzymes, glutathione peroxidase and catalase, and reduced plasma lipid peroxidation. In conclusion, BR supplementation may decrease cigarette smoke-induced oxidative stress through increase of endogenous antioxidant enzyme activities.

Bibliographic Details

Eunkyo Park; Jung eun Lee; Yesl Kim; Min Sun Go; Jung Hyun Kim; Soo Muk Cho; Seung Min Lee; Young Jae Kim; In Kyung Jung; Joong Hyuck Auh; Hyung Kyoon Choi

Elsevier BV

Agricultural and Biological Sciences; Medicine; Nursing

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