NDM-1- and OXA-163-producing Klebsiella pneumoniae isolates in Cairo, Egypt, 2012
Journal of Global Antimicrobial Resistance, ISSN: 2213-7165, Vol: 1, Issue: 4, Page: 213-215
2013
- 35Citations
- 60Captures
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Example: if you select the 1-year option for an article published in 2019 and a metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019. If you select the 3-year option for the same article published in 2019 and the metric category shows 90%, that means that the article or review is performing better than 90% of the other articles/reviews published in that journal in 2019, 2018 and 2017.
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Metrics Details
- Citations35
- Citation Indexes35
- 35
- CrossRef22
- Captures60
- Readers60
- 60
Article Description
Here we describe carbapenem resistance determinants in two Klebsiella pneumoniae isolates recovered from two hospitalised patients in the same intensive care unit of a cancer hospital in Cairo, Egypt. PCR and sequencing were used to detect and characterise β-lactamase genes. Clonal relationships between the isolates were analysed by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST). The first K. pneumoniae isolate carried the bla NDM-1 gene and the second isolate carried the bla OXA-163 gene. Both isolates co-expressed the extended-spectrum β-lactamase CTX-M-15. The two isolates belonged to different sequence types (STs), ST11 and ST16, respectively. No history of travel was established for the two patients. The first identification of NDM-1-producing K. pneumoniae in Egypt adds further evidence to the spread of NDM-1-producing Gram-negative micro-organisms in North Africa. The additional detection of bla OXA-163 in a K. pneumoniae isolate confirms its endemic presence in a critical healthcare setting of this geographic area.
Bibliographic Details
http://www.sciencedirect.com/science/article/pii/S2213716513000684; http://dx.doi.org/10.1016/j.jgar.2013.06.003; http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84890328053&origin=inward; http://www.ncbi.nlm.nih.gov/pubmed/27873615; https://linkinghub.elsevier.com/retrieve/pii/S2213716513000684; https://dx.doi.org/10.1016/j.jgar.2013.06.003
Elsevier BV
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